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Which major factor differentiates DNA from RNA?

Correct Answer: D — Uracil

In RNA, uracil replaces thymine as the usual complement of adenine. Thus, thymine is usually seen only in DNA and uracil only in RNA. Methylation of uracil produces thymine, providing a mechanism for repair and protection of DNA and improvement of DNA replication. One of the common mutations of DNA involves two adjacent thymines.