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Gentamycin is an aminoglycoside antibiotic that is known for its effectiveness against a broad spectrum of bacterial infections. However, its use is limited by its potential to cause nephrotoxicity (kidney damage) and ototoxicity (hearing loss). Nephrotoxicity occurs because Gentamycin can accumulate in the renal cortex, leading to damage of the kidney cells. This often manifests as an increase in serum creatinine and blood urea nitrogen levels, indicating impaired kidney function. Ototoxicity is another serious side effect, resulting from the drug’s accumulation in the inner ear, which can lead to both vestibular (balance) and auditory (hearing) dysfunction. Symptoms may include tinnitus (ringing in the ears), vertigo, and hearing loss.

**_ Penicillin is a beta-lactam antibiotic that is generally well-tolerated. Its most common side effects are allergic reactions, including rashes, fever, and, in severe cases, anaphylaxis. It is not typically associated with nephrotoxicity or ototoxicity. Chloramphenicol is an antibiotic that can cause serious side effects, including bone marrow suppression leading to aplastic anemia. However, it is not commonly linked to nephrotoxicity or ototoxicity. Ethambutol is an antitubercular drug that can cause optic neuritis, leading to visual disturbances. Nephrotoxicity and ototoxicity are not primary concerns with this medication. Among the given options, Gentamycin is the antibiotic associated with nephrotoxicity and ototoxicity. It is crucial to monitor patients on Gentamycin for signs of kidney damage and hearing loss to mitigate these serious side effects.